Faculty

GUO Zhenxing

Associate Professor

Hematology / Oncology

Beijing Huaxin Hospital

gzx2962@outlook.com

Education and Employment

Education experience

2005.8-2008.7 CAMS&PUMC Hematology MD

2001.8-2004.7 Zhejiang University Hematology Master

1996.8-2001.7 Shanxi Medical University Clinic medicine Bachelor

Working experience

2019.12- Present Head, Chief Physician/Associate Professor

Department of Hematology/Oncology, First Hospital of Tsinghua University

2019. 4 -2019.6 Visiting scholar

Edinburgh University, Western General Hospital

2015.3- Present Head, Associate physician

Department of Hematology/Oncology, First Hospital of Tsinghua University

2012.12-2019.12 Associate physician

Department of Hematology/Oncology, First Hospital of Tsinghua University

2009.12 -2012.12 Attending

Department of Hematology/Oncology, First Hospital of Tsinghua University

2008.8 -2009.12 Resident

Department of Hematology/Oncology, First Hospital of Tsinghua University

2004.7-2005.8 Resident

Department of Hematology, Ningbo First Hospital

Research Field

Pathogenesis of malignant hematological tumors

Immune regulation mechanism of stem cell

Selected Publications

1 Liao M, Chen R, Yang Y, He H, Xu L, Jiang Y, Guo Z, He W, Jiang H, Wang J. Aging-elevated inflammation promotes DNMT3A R878H-driven clonal hematopoiesis. Acta Pharmaceutica Sinica B. 2022; 12(2):678-691.

2 Liao M, Dong Q, Chen R, Xu L, Jiang Y, Guo Z, Xiao M, He W, Cao C, Hu R, Sun W, Jiang H, Wang J. Oridonin inhibits DNMT3A R882 mutation-driven clonal hematopoiesis and leukemia by inducing apoptosis and necroptosis. Cell Death Discov. 2021 Oct 18;7(1):297.

3 Wang F, Xu W, Liu L, Ren X, Liu P, Zheng L, Zhang H, Zhang S, Xu Y, Guo Z*. Low dose of homoharringtonine and cytarabinebased priming induction regimens for patients with de novo acute myeloid leukemia and highrisk myelodysplastic syndrome aged over 70 years. Hematology. 2021;26(1):1040-1045.

4 Guo Z*, Chen Z, Xu Y, Zhang Y, Hu L, Yu F, Chai J, Liu L, Ren X. The Association of Circulating T Follicular Helper Cells and Regulatory Cells with Acute Myeloid Leukemia Patients. Acta Haematol. 2020; 143(1):19-25.

5 Zhang S, Guo Z*. Case report of a primary prostatic urothelial carcinoma patient with sustained fever. Onco Targets Ther. 2018;11:4547-4550.

6 Guo Z*, Liang H, Xu Y, Liu L, Ren X, Zhang S, Wei S, Xu P. The Role of Circulating T Follicular Helper Cells and Regulatory Cells in Non-Small Cell Lung Cancer Patients. Scand J Immunol. 2017;86(2):107-112.

7 Chen Z, Guo Z, Ma J, Liu F, Gao C, Liu S, Wang A, Wu R. STAT1 single nucleotide polymorphisms and susceptibility to immune thrombocytopenia. Autoimmunity. 2015,24:1-8.

8 Chen Z, Guo Z, Ma J, Ma J, Liu F, Wu R.Foxp3 methylation status in children with primary immune thrombocytopenia. Hum Immunol. 2014;75(11):1115-9.

9 Guo Z, Zheng C, Chen Z, Gu D, Du W, Ge J, Han Z, Yang R.Fetal bone marrow-derived mesenchymal stem cells promote the expansion of human Th17 cells, but inhibit the production of Th1 cells. Eur J Immunol. 2009,39:2840-2849.

10 Guo ZX, Chen ZP, Zheng CL, Jia HR, Ge J, Gu DS, Du WT, Wang XY, Zhao HF, Yang RC.The role of Th17 cells in adult patients with chronic idiopathic thrombocytopenic purpura. Eur J Haematol.2009,6:488-9.

Awards and Membership

"Academic Award" and "Good Doctor" title from the First Hospital of Tsinghua University

Member of Leukemia Professional Committee of Chinese Medical Education Association

Member of Hematology Branch of Beijing Medical Association

Member of Abdominal Tumor Professional Committee of Chinese Medical Education Association

Expert in project evaluation of Beijing Municipal Science and Technology Commission

学术任职

2019年7月-至今,朝阳区医疗技术鉴定专家

2018年6月-至今,北京中西医结合学会第二届血液学专业委员会常务委员

2018年6月-至今,京津冀中西医结合血液病联盟第一届理事会,理事

2018年4月-至今,北京医师协会血液内科医师分会,理事

2017年8月-至今,中国医药教育协会血液学专业委员会,委员

2017年4月-至今,北京抗癌协会癌症康复与姑息治疗专业委员会,青年委员

2011年12月-2013年12月,《中国组织工程研究与临床康复》杂志 执行编委

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