Faculty

ZHAO Xiuying

Professor

Clinical Laboratory Diagnostics

Beijing Tsinghua Changgung Hospital

zxya00340@btch.edu.cn

Education Background

· Jun 2005: Ph.D. in Microbiology, The University of Hong Kong

· Jul 1999: Master of Medical Science in Infectious Diseases, Capital Medical University

· Jul 1991: Bachelor of Medical Science, Inner Mongolia Medical College

Work Experience

Oct 2012 – Present:

· Director, Department of Laboratory Medicine, Beijing Tsinghua Changgung Hospital

Responsibilities include laboratory management, discipline development, experimental diagnosis and pathogenesis research of infectious and immune-related diseases, and diagnostic technology research.

· Chief Physician, Department of Gastroenterology

Specializing in the diagnosis and treatment of digestive system infectious diseases.

Jul 1991 – Sep 2012:

· Beijing You’an Hospital, Capital Medical University

Served as Resident Physician, Attending Physician, Associate Chief Physician, and Chief Physician.

From 2005, served as Deputy Director of the Clinical Testing Center.

Long-term engagement in the diagnosis and treatment of viral infections, as well as research in immunological and molecular diagnostics.

Research Interests

1. Experimental diagnosis and pathogenesis of infectious and immune-related diseases.

2. Diagnostic technologies.

3. Lean management of clinical laboratories.

Representative Publications

Published 80 papers as first or corresponding author and edited/co-edited 2 monographs. Selected publications:

1. Lok CH, Zhu D, Wang J, Ren YT, Jiang X, Li SJ, Zhao XY(corresponding author)Phenotype and molecular detection of Clarithromycin and Levofloxacin resistance in Helicobacter pylori clinical isolates in Beijing,Infection and Drug Resistance. 2020:13. 2145-2153.

2. DONG JX, LI AF LI RQ, CHAO S, YANG S, ZHAO XY(corresponding author).Epidemiological and clinical features of Rotavirus and Adenovirus related gastroenteritis in Beijing: a retrospective case-control study in pediatric patients, Biomed Environ Sci, 2020; 33(3):196-200. SCI 1.917

3. Xiao N, Gai W, Hu WG, Li JX, Zhang Y, Zhao XY (co-corresponding author). Next-generation-sequencing technology helped detecting the Mycoplasma hominis from the drainage of renal cyst: a case report, Infection and Drug Resistance. 2019. May,12:1073-1079

4. Yao Y, Zhao ZP, Song WQ, Li RQ, Zhu D, Qin K, Zhao XY (co-corresponding author).Unreliable usage of a single influenza virus IgM antibody assay in influenza-like illness (ILI) cases, a retrospective study about 2016-2018 Winter flu epidemic, Plos One Apr 2019;https://doi.org/10.1371/journal.pone.0215514

5. Zhu D, Lok CH, Chao S, Chen LL, Li RQ, Zhao ZP, Dong JX, Qin K and Zhao XY (co-corresponding author). Detection and characterizations of type B influenza virus from ILI cases during 2017-2018 winter flu season in Beijing, China. Archives of Virology 2019 Apr, 164 (4): 995-1003

6.Zhao XY (corresponding author), Zhu D, Zhang HJ, Sui HY, Poon V, Li N, Jiang SB and Zheng BJ. A nature “GA” inserts mutation in G-Quadraplexs of CXCL12/SDF-1α 3’UTR: Identification, characterization, and its functional impacts on gene splicing and expression. Gene 681(2019):36-44

7. Zhao XY (corresponding author), Zeng ZY, Hua WH, Yu YH, Guo CP, Dong HY, Wan KL. Retrospective Study of Culture-confirmed Mycobacteria Infection among Hospitalized HIV-infected Patients in Beijing, China. Biomed Environ Sci, 2018; 31(6):459-463

8. LIU J, Wang HZ, LIAN LL, YU YH, ZHAO XQ, GUO CP,LIU HC, LIU SM, ZHAO H, ZENG ZY, ZHAO XY (co-corresponding author), and WAN KL. Molecular Characteristics and Drug Susceptibility of Mycobacterium tuberculosis Isolates from Patients Co-infected with Human Immunodeficiency Virus in Beijing, China. Biomed Environ Sci, 2015

9. Yu YH, Zhao XY(co-first author),Wang W, Wu H, Chen M, Hua WH, Wang HZ,Wei T, Jiao JM, Sun GZ, Li W. Diagnostic Performance of Interferon-Gamma Releasing Assay in HIV-Infected Patients in China. Plos One 2013(8):e70957

10. Zhu D,Zhao XY(corresponding author),Yao Y, Dai FF, He H, Li RQ, Jin RH, Liang LC and Li N. A new factor influencing pathogen detection by molecular assay in children with both mild and severe hand, foot and mouth disease Diagnostic Microbiology and Infectious Disease,2013,76(3):162-167

11.Zhao XY, Lee SS, Wong KH, Chan KCW, Ng F, Chan CCS, Han D, Yam WC, Yuen KY, Ng MH, Zheng BJ. Functional analysis of naturally occurring mutations in open reading frame of CCR5 in Chinese HIV patients and healthy controls.JAIDS. 38:509-517. 2005

12.Zhao XY, Lee SS, Wong KH, Chan KCW, He ZM, Ma S, Ng F, Chan CCS, Ho T, Ng MH, Zheng BJ. A novel CCR5 mutation selectively affects immunoreactivity and fusogenic property of the HIV co-receptor in a slow progressing HIV patient.AIDS. 18:1729-1732. 2004

Academic Honors & Awards

· 2011: Selected for the Beijing Municipal Health Bureau’s "Ten-Hundred-Thousand" Talent Cultivation Program (Tier "Hundred").

· Discipline Backbone of the Beijing Health System’s "215" High-Level Health Technical Talent Cultivation Program.

Academic Appointments

1. Member, Chinese Medical Association – Society of Microbiology and Immunology.

2. Member, Chinese Medical Doctor Association – Society of Laboratory Physicians.

3. Standing Committee Member, Beijing Medical Association – Society of Laboratory Medicine.

4. Vice Chairman, Beijing Association of Integrative Medicine – Society of Laboratory Medicine.

5. Executive Director, Beijing Medical Doctor Association – Society of Laboratory Physicians.

6. Standing Committee Member, Beijing Medical Association – Society of Infection and Immunology.

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