Home >> Faculty >> Faculty List >> Tenure Track >> Content

Faculty

WEI Lai

Professor

Gastroenterology

Beijing Tsinghua Changgung Hospital

School of Clinical Medicine, Tsinghua University

weilai@mail.tsinghua.edu.cn

Education Background

Oct. 1978-Jul. 1983 Bachelor’s Degree, Xuzhou Medical University

Sept. 1986-Jun. 1989 Master’s Degree, Xuzhou Medical University

Sept. 1993-Jun. 1996 Doctoral Degree, Peking University Health Science Center (Former Peking Medical University)

Professional Experience

Jul. 1983-Oct. 2000 The Affiliated Hospital of Xuzhou Medical University

Nov. 2000-Feb. 2019 Peking University People’s Hospital

Mar. 2019-Present Beijing Tsinghua Changgung Hospital

Research Field

1. Diagnosis of Nonalcoholic Fatty Liver Diseas

2. Antiviral Therapy for Chronic Hepatitis B

Selected Publications

1. Sofosbuvir-velpatasvir for treatment of chronic hepatitis C virus infection in Asia: a single-arm, open-label, phase 3 trial.Lancet Gastroenterol Hepatol.2019 Feb;4(2):127-134.

2. Hepatitis B Virus Virions Produced Under Nucleos(t)ide Analogue Treatment Are Mainly Not Infectious Because of Irreversible DNA Chain Termination.Hepatology. 2020 Feb;71(2):463-476.

3. qFIBS: An Automated Technique for Quantitative Evaluation of Fibrosis, Inflammation, Ballooning, and Steatosis in Patients With Nonalcoholic Steatohepatitis. Hepatology. 2020 Jun;71(6):1953-1966.

4. Glecaprevir-pibrentasvir to treat chronic hepatitis C virus infection in Asia: two multicentre, phase 3 studies- a randomised, double-blind study (VOYAGE-1) and an open-label, single-arm study (VOYAGE-2). Lancet Gastroenterol Hepatol. 2020 Jul 16:S2468-1253(20)30086-8. doi: 10.1016/S2468-

Academic Honors and Awards

Second Prize of Chinese Medical Science and Technology Award,

Second Prize of the Ministry of Education Science and Technology Progress Award,

Second Prize of Beijing Municipal Science and Technology Progress Award

Led national key scientific and technological programs under the 10th, 11th, and 12th Five-Year Plans. Developed optimized treatment protocols for chronic hepatitis C, which have been incorporated into the WHO Guidelines, the APASL Guidelines, and China’s Guidelines for the Prevention and Treatment of Chronic Hepatitis C. Established the industry standard Screening and Management of Hepatitis C based on the epidemiological features in China, which is recommended in the National Action Plan for Eliminating the Public Health Threat of Hepatitis C (2021–2030) issued by the National Health Commission and nine other ministries. Currently leading a national key R&D program to develop a non-staining, fully automated, AI-powered, quantitative system for multi-dimensional assessment of liver histology in NAFLD, which has been adopted by the AASLD Guidelines on NAFLD and used by multiple multinational pharmaceutical companies for drug efficacy evaluation. Also led a sub-project under the 973 Program on redefining the threshold for hepatitis B surface antigen seroclearance, which has been incorporated into the EASL Guidelines on Hepatitis B. These research results have been published in Gastroenterology, Lancet Gastroenterology and Hepatology, and Hepatology.

Membership

President, Asia-Pacific Association for the Study of the Liver (March 30, 2024-March 30, 2025)

Member, WHO Strategic and Technical Advisory Group on Viral Hepatitis

Honorary Chair, Hepatology Branch, Chinese Medical Association

Deputy Editor, Clinical Gastroenterology and Hepatology

Deputy Editor, iLiver

Deputy Editor, Journal of Viral Hepatitis

Deputy Editor, Journal of Clinical and Translational Hepatology

TOP