Faculty

MA Yu

Professor

Neurosurgery

Tsinghua University Yuquan Hospital

Mayu@tsinghua.edu.cn

Education & Training

· 2007: Earned MD/PhD from China Medical University

· 2007-2009: Postdoctoral fellowship under Professor Wang Zhongcheng (Academician of Chinese Academy of Engineering) and Professor Zhang Jianguo at Beijing Tiantan Hospital

Work Experience

With over 15 years of specialized experience in deep brain stimulation (DBS) for movement disorders (Parkinson's disease, dystonia, Tourette syndrome, etc.), I have developed comprehensive expertise in:

· Preoperative assessment

· Intraoperative neurophysiological monitoring

· Postoperative programming

· Pharmacological management

Key Clinical Contributions

· Served as principal investigator for China's first domestically developed DBS systems:

o 1st generation (unilateral non-rechargeable)

o 2nd generation (bilateral rechargeable)

· Performed >1,000 DBS surgeries

· Conducted >10,000 postoperative programming sessions

· Pioneered integrated psychological intervention protocols for DBS patients through advanced training at Chinese Academy of Sciences (2012)

Research Leadership

Completed Grants:

1. China Postdoc Science Foundation (20070420399):

o DBS of nucleus accumbens for opioid addiction (PI)

2. Beijing Nova Program (2008B43):

o Mechanisms of DBS for dystonia (PI)

3. NSFC Director's Fund (81141013):

o Neuroprotective effects of DBS in Alzheimer's models (PI)

Major Collaborative Projects:

· National 11th Five-Year Plan (2006BAI03A18):

o Development of domestic DBS devices (Key contributor, Rank 4)

Selected Publications

1. Vision-Based Method for Automatic Quantification of Parkinsonian Bradykinesia. JOURNAL OF LATEX CLASS FILES.2019,14(8):2961-2965.Tianpeng Li, Weitao Wan, Yiqing Huang, Jiansheng Chen, Chunhua Hu, and Yu Ma.

2. Predicting the Post-therapy Severity Level (UPDRS-III) of Patients With Parkinson's Disease After Drug Therapy by Using the Dynamic Connectivity Efficiency of fMRI. Front Neurol,2019,10(3):668-677.Xuesong Li, Yuhui Xiong, Simin Liu , Rongsong Zhou, Zhangxuan Hu,Yan Tong, Le He, Zhendong Niu, Yu Ma and Hua Guo.

3. sEMG-Based Tremor Severity Evaluation for Parkinson’s Disease Using a Light-Weight CNN. IEEE Signal Processing Letters,2019,26(4):637-641 Zengyi Qin, Zhenyu Jiang, Jiansheng Chen , Chunhua Hu, and Yu Ma.

4. An Intraoperative Multibranch Abnormal Muscle Response Monitoring Method During Microvascular Decompression for Hemifacial Spasm.World Neurosurgery,2019,117:280-283. Suhua Miao, Ying Chen, Xinxin Hu, Rongsong Zhou, Yu Ma.

5. Improving Human Parsing by Extracting Global Information Using the Non-Local Operation. 2019 IEEE International Conference on Image Processing (ICIP), Taipei, Taiwan, 22-25 Sept. 201 Tianpeng Li, Weitao Wan, Yiqing Huang, Jiansheng Chen, Chunhua Hu, and Yu Ma

6. Long-Term Effect of Modified Incision to Prevent Related Complications in Deep Brain Stimulation. World Neurosurg. 2018, 117:280-283 Rongsong Zhou, Yu Ma, Wei Liu, Suhua Miao, Yuqi Zhang.

7. Application of electrophysiological methods and magnetic resonance tomographic angiography in the differentiation between hemifacial spasm and Meige syndrome[J]. Neurological Sciences, 2016, 37(5): 769-775. Huang C, Miao S, Chu H, Muheremu A, Wu J, Zhou R, Zuo H, Ma Y. *

8. An optimized abnormal muscle response recording method for intraoperative monitoring of hemifacial spasm and its long-term prognostic value[J]. International Journal of Surgery, 2017, 38: 67-73. Huang C, Miao S, Chu H, Dai C, Wu J, Wang J, Zuo H, Ma Y*.

9. 7.0 T nuclear magnetic resonance evaluation of the amyloid beta (1–40) animal model of Alzheimer's disease: comparison of cytology verification[J]. Neural regeneration research, 2014, 9(4): 430.Zhang L, Dong S, Zhao G, Ma Y*.

10.High-frequency stimulation of nucleus accumbens changes in dopaminergic reward circuit[J]. PloS one, 2013, 8(11): e79318. Yan N, Chen N, Zhu H, Zhang J, Sim M, Ma Y*, Wang W..

Honors

· 2010: 2nd Prize, Outstanding Scientific Research Award (Ministry of Education)

o DBS mechanisms in extrapyramidal diseases (Rank 2)

· 2009: 3rd Prize, Chinese Medical Science & Technology Award

o DBS for movement disorders (Rank 4)

Professional Service

· Expert Committee Member: Neurophysiology Branch, Chinese Association of Neurosurgeons

· Standing Committee Member: Geriatric Neurophysiology Committee, China Association of Gerontology

· Youth Committee Member: Beijing Neurosurgical Society

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