Faculty

GUO Zhenxing

Associate Professor

Hematology / Oncology

Beijing Huaxin Hospital

gzx2962@outlook.com

Education and Employment

Education experience

2005.8-2008.7 CAMS&PUMC Hematology MD

2001.8-2004.7 Zhejiang University Hematology Master

1996.8-2001.7 Shanxi Medical University Clinic medicine Bachelor

Working experience

2019.12- Present Head, Chief Physician/Associate Professor

Department of Hematology/Oncology, First Hospital of Tsinghua University

2019. 4 -2019.6 Visiting scholar

Edinburgh University, Western General Hospital

2015.3- Present Head, Associate physician

Department of Hematology/Oncology, First Hospital of Tsinghua University

2012.12-2019.12 Associate physician

Department of Hematology/Oncology, First Hospital of Tsinghua University

2009.12 -2012.12 Attending

Department of Hematology/Oncology, First Hospital of Tsinghua University

2008.8 -2009.12 Resident

Department of Hematology/Oncology, First Hospital of Tsinghua University

2004.7-2005.8 Resident

Department of Hematology, Ningbo First Hospital

Research Field

Pathogenesis of malignant hematological tumors

Immune regulation mechanism of stem cell

Selected Publications

1 Liao M, Chen R, Yang Y, He H, Xu L, Jiang Y, Guo Z, He W, Jiang H, Wang J. Aging-elevated inflammation promotes DNMT3A R878H-driven clonal hematopoiesis. Acta Pharmaceutica Sinica B. 2022; 12(2):678-691.

2 Liao M, Dong Q, Chen R, Xu L, Jiang Y, Guo Z, Xiao M, He W, Cao C, Hu R, Sun W, Jiang H, Wang J. Oridonin inhibits DNMT3A R882 mutation-driven clonal hematopoiesis and leukemia by inducing apoptosis and necroptosis. Cell Death Discov. 2021 Oct 18;7(1):297.

3 Wang F, Xu W, Liu L, Ren X, Liu P, Zheng L, Zhang H, Zhang S, Xu Y, Guo Z*. Low dose of homoharringtonine and cytarabinebased priming induction regimens for patients with de novo acute myeloid leukemia and highrisk myelodysplastic syndrome aged over 70 years. Hematology. 2021;26(1):1040-1045.

4 Guo Z*, Chen Z, Xu Y, Zhang Y, Hu L, Yu F, Chai J, Liu L, Ren X. The Association of Circulating T Follicular Helper Cells and Regulatory Cells with Acute Myeloid Leukemia Patients. Acta Haematol. 2020; 143(1):19-25.

5 Zhang S, Guo Z*. Case report of a primary prostatic urothelial carcinoma patient with sustained fever. Onco Targets Ther. 2018;11:4547-4550.

6 Guo Z*, Liang H, Xu Y, Liu L, Ren X, Zhang S, Wei S, Xu P. The Role of Circulating T Follicular Helper Cells and Regulatory Cells in Non-Small Cell Lung Cancer Patients. Scand J Immunol. 2017;86(2):107-112.

7 Chen Z, Guo Z, Ma J, Liu F, Gao C, Liu S, Wang A, Wu R. STAT1 single nucleotide polymorphisms and susceptibility to immune thrombocytopenia. Autoimmunity. 2015,24:1-8.

8 Chen Z, Guo Z, Ma J, Ma J, Liu F, Wu R.Foxp3 methylation status in children with primary immune thrombocytopenia. Hum Immunol. 2014;75(11):1115-9.

9 Guo Z, Zheng C, Chen Z, Gu D, Du W, Ge J, Han Z, Yang R.Fetal bone marrow-derived mesenchymal stem cells promote the expansion of human Th17 cells, but inhibit the production of Th1 cells. Eur J Immunol. 2009,39:2840-2849.

10 Guo ZX, Chen ZP, Zheng CL, Jia HR, Ge J, Gu DS, Du WT, Wang XY, Zhao HF, Yang RC.The role of Th17 cells in adult patients with chronic idiopathic thrombocytopenic purpura. Eur J Haematol.2009,6:488-9.

Awards and Membership

"Academic Award" and "Good Doctor" title from the First Hospital of Tsinghua University

Member of Leukemia Professional Committee of Chinese Medical Education Association

Member of Hematology Branch of Beijing Medical Association

Member of Abdominal Tumor Professional Committee of Chinese Medical Education Association

Expert in project evaluation of Beijing Municipal Science and Technology Commission

Academic Appointments

  • Committee Member, Hematology Professional Committee, China Medicine Education Association

  • Committee Member, Leukemia Professional Committee, China Medicine Education Association

  • Committee Member, Hematology Branch, Beijing Medical Association

  • Council Member, Hematology Physician Branch, Beijing Medical Doctor Association

  • Standing Committee Member, Hematology Professional Committee, Beijing Association of Integrative Medicine

  • Standing Committee Member, Thrombosis and Hemostasis Professional Committee, Beijing Cancer Prevention and Treatment Society

  • Council Member, Beijing-Tianjin-Hebei Alliance of Integrative Hematology

  • Committee Member, Abdominal Tumor Professional Committee, China Medicine Education Association

  • Committee Member, Breast Cancer Branch, Beijing Cancer Prevention and Treatment Research Association

  • Vice Chairman, Hematology Committee, Beijing Chaoyang District Preventive Medicine Association

  • Project Review Expert, Beijing Municipal Science & Technology Commission

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