Faculty

Stem Cells and Regenerative Medicine;

Tissue Engineering;

Translational Medical Research;

Precision Medicine.

1. Wang, S.; Wang, X.; Shan, Y.; Tan, Z.; Su, Y.; Cao, Y.; Wang, S.; Dong, J.; Gu, J.; Wang, Y.*, Region-specific cellular and molecular basis of liver regeneration after acute pericentral injury. Cell Stem Cell 2024, doi.org/10.1016/j.stem.2024.01.013.

2. Jia, H.; Liu, J.; Fang, T.; Zhou, Z.; Li, R.; Yin, W.; Qian, Y.; Wang, Q.; Zhou, W.; Liu, C.; Sun, D.; Chen, X.; Ouyang, Z.; Dong, J.; Wang, Y.*; Yue, S., The role of altered lipid composition and distribution in liver fibrosis revealed by multimodal nonlinear optical microscopy. Sci Adv 2023, 9 (2), eabq2937.

3. Li, R.; Liu, J.; Ma, J.; Sun, X.; Wang, Y.; Yan, J.; Yu, Q.; Diao, J.; Yang, C.; Reid, L. M.; Wang, Y.*, Fibrinogen improves liver function via promoting cell aggregation and fibronectin assembly in hepatic spheroids. Biomaterials 2022, 280, 121266.

4. Wang, S.; Wang, X.; Tan, Z.; Su, Y.; Liu, J.; Chang, M.; Yan, F.; Chen, J.; Chen, T.; Li, C.; Wang, Y.*, Human ESC-derived expandable hepatic organoids enable therapeutic liver repopulation and pathophysiological modeling of alcoholic liver injury. Cell Research 2019, 29 (12), 1009-1026.

5. Yan, F.; Wang, Y.; Zhang, W.; Chang, M.; He, Z.; Xu, J.; Shang, C.; Chen, T.; Liu, J.; Wang, X.; Pei, X.; Wang, Y.*, Human embryonic stem cell–derived hepatoblasts are an optimal lineage stage for hepatitis C virus infection. Hepatology 2017, 66 (3), 717-735.

6. Wang, Y.; Qin, J.; Wang, S.; Zhang, W.; Duan, J.; Zhang, J.; Wang, X.; Yan, F.; Chang, M.; Liu, X.; Feng, B.; Liu, J.; Pei, X., Conversion of human gastric epithelial cells to multipotent endodermal progenitors using defined small molecules. Cell Stem Cell 2016, 19 (4), 449-461.

7. Cardinale, V.#; Wang, Y.#; Carpino, G.; Mendel, G.; Alpini, G.; Gaudio, E.; Reid, L. M.; Alvaro, D., The biliary tree--a reservoir of multipotent stem cells. Nat Rev Gastroenterol Hepatol 2012, 9 (4), 231-240.

8. Wang, Y.; Cui, C. B.; Yamauchi, M.; Miguez, P.; Roach, M.; Malavarca, R.; Costello, M. J.; Cardinale, V.; Wauthier, E.; Barbier, C., Lineage restriction of human hepatic stem cells to mature fates is made efficient by tissue‐specific biomatrix scaffolds. Hepatology 2011, 53 (1), 293-305.

9. Cardinale, V.#; Wang, Y.#; Carpino, G.; Cui, C. B.; Gatto, M.; Rossi, M.; Berloco, P. B.; Cantafora, A.; Wauthier, E.; Furth, M. E.; Inverardi, L.; Dominguez-Bendala, J.; Ricordi, C.; Gerber, D.; Gaudio, E.; Alvaro, D.; Reid, L., Multipotent stem/progenitor cells in human biliary tree give rise to hepatocytes, cholangiocytes, and pancreatic islets. Hepatology 2011, 54 (6), 2159-72.

10. Wang, Y.; Yao, H. L.; Cui, C. B.; Wauthier, E.; Barbier, C.; Costello, M. J.; Moss, N.; Yamauchi, M.; Sricholpech, M.; Gerber, D., Paracrine signals from mesenchymal cell populations govern the expansion and differentiation of human hepatic stem cells to adult liver fates. Hepatology 2010, 52 (4), 1443-1454.

11. The liver: Biology and Pathobiology, translated by Dong Jiahong and Wang Yunfang, China Science and Technology Press, 2024

In 2024, awarded the First prize in the Fourth China Science and Technology Industrialization Promotion Association Standard Innovation.

In 2023, recipient of the special government allowance of The State Council.

In 2022, recognized as a high-level public health technical leader by the Beijing Municipal Health Commission.

In 2021, awarded the China Toxicology Alternative Methods Development Award.

In 2020, selected for the "Millions of Talents Project" at the national level and honored with the title of Young and Middle-aged Scientist with Outstanding Contributions.

In 2019, selected for the "Summit Plan" by the Beijing Municipal Hospital Administration Center.

In 2018, awarded the First Prize in Military Science and Technology Progress.

In 2014, awarded the First Prize in Beijing Science and Technology.

In 2007, awarded the Second Prize in National Science and Technology Progress.

Associate Editor of iLiver journal

Editorial Board member of Research magazine

Member of the Editorial Board of Hepatology journal;

Deputy Director, Organoid Branch, Chinese Society of Genetics（2024-）

Member of the Professional Committee of Clinical Data and Sample Resource Bank of Chinese Research Hospital Society（2024-）

Member of the Expert Committee of the China Consortium for Research on Aging Biomarkers (2023-)

Committee member of the Cell Therapy Research and Application Branch of the Chinese Society for Cell Biology (2023-)

Committee member of the Organ Biobank Branch of the China Medicinal Biotech Association and Deputy Leader of the Organoid Study Group (2023-)

Council member of the Translational Medicine Branch of the Chinese Research Hospital Association (2016-)

Tel: 010-56112316

Email: wangyf008@mail.tsinghua.edu.cn